If you’ve been researching dermal fillers for smile lines and facial folds, you’ve probably come across Restylane® Refyne and Restylane® Defyne — but what’s the difference, and which one is right for you?
At Genesis Plastic Surgery & Medical Spa, both fillers are available and administered with precision. Treatments are overseen by Dr. Jayesh Panchal, a board-certified plastic surgeon who is known for his thoughtful, patient-centered approach and commitment to natural-looking results.
In this blog, you’ll learn how Restylane Refyne and Restylane Defyne work, what areas they treat, and how to decide which option best fits your goals.
What Are Restylane Refyne and Restylane Defyne?
Restylane Refyne and Restylane Defyne are hyaluronic acid (HA) dermal fillers designed to smooth moderate to severe facial wrinkles and folds.
Both Refyne and Defyne use XpresHAn Technology™, which allows the filler to move naturally. That means you can smile, laugh, and talk without seeming stiff or “overfilled.”
Restylane Refyne: Best for Moderate Lines
Restylane Refyne is typically used for:
- Mild to moderate smile lines (nasolabial folds)
- Marionette lines
- Subtle volume loss around the mouth
Refyne is softer and more flexible. It works well for patients who want gentle smoothing while maintaining facial movement. It’s often a good option for those in earlier stages of volume loss.
Restylane Defyne: Built for Deeper Folds
Restylane Defyne is slightly firmer and provides more structural support. It’s commonly used for:
- Moderate to severe nasolabial folds
- Deeper marionette lines
- Chin projection and definition (FDA-approved for chin augmentation in adults over 21)
Because Defyne offers greater lift and support, it’s often recommended for more pronounced wrinkles or when facial contouring is desired.
How Long Do Results Last?
Both fillers can last up to 12 months, though this varies depending on:
- Your metabolism
- Treatment area
- Amount of product used
- Lifestyle factors
Effects are visible almost immediately, and you’ll see continued improvement as swelling settles over several days.
Schedule a Restylane Consultation Today
Choosing between Restylane Refyne and Restylane Defyne doesn’t have to feel overwhelming. With the right guidance, you can fill in lines and refresh contours while still looking like yourself.
Call Genesis Plastic Surgery & Medical Spa in Edmond at 405-340-9949 or in Norman at 405-310-6767 to schedule a consultation and learn which Restylane filler is right for you.